Gold Nanostructures for Cancer Treatment

With cancer currently one of the most fatal diseases in the world, it is important to develop effective methods of detection and treatment, which would allow for quick diagnosis and efficient treatment that is of little discomfort to patients. Gold nanostructures with near infrared absorption may be the most promising solution, due to their ability … Read more

Nanotherapeutics

1. Introduction Nanotherapeutics is a rapidly progressing area in the field of Nanomedicine, which is being utilized to overcome several limitations of conventional drug, including poor aqueous solubility, lack of site specific targeting, rapid systemic clearance, intestinal metabolism and systemic toxicities. Nanotherapeutics includes, but not limited to, solid-lipid nanoparticles, gold nanoparticles, silver nanoparticles, mesoporous silica … Read more

Malaria

Chapter I Introduction: Malaria is a life-threatening disease and is widespread in the tropical and subtropical regions mainly around the equator. Malaria is a protozoan disease and transmitted through infected female anopheles mosquitoes. There are five Plasmodium species which can infect human beings namely Plasmodium falciparum (Pf), Plasmodium vivax (Pv), Plasmodium malariae (Pm), Plasmodium ovale … Read more

Peripheral Vascular Disease

Summary of Disease Processes Priority medical diagnosis: Peripheral Vascular Disease Peripheral vascular disease includes all vascular disorders of the blood vessel system outside of the heart. Acute and chronic vascular diseases may develop progressively from atherosclerotic plaque formation. Atherosclerosis is defined as the process of fatty substances, cholesterol, cellular waste products, calcium, and fibrin building … Read more

Definitive control of the airway

Definitive control of the airway, a skill anaesthesiologists now consider paramount, developed only after many harrowing and apneic episodes spurred the development of safer airway management techniques1[barash pg no 7]. Anaesthesiologists who practised before muscle relaxants recall the anxiety they felt when a premature attempt to intubate the trachea under cyclopropane caused persisting laryngospasm[ barash … Read more

Management of trauma

Management of trauma has always been one of the surgical subsets in which oral and maxillofacial surgeons over the years. The mandibular body is a parabola-shaped curved bone composed of external and internal cortical layers surrounding a central core of cancellous bone. The goals of treatment, are to restore proper function by ensuring union of … Read more

Inflammatory bowel disease (IBD)

What is IBD? Inflammatory bowel disease is a chronic disease which is dominated by inflammation in the gut. The inflammation is the result of an immune system defects inducing the production of adhesion molecules and inflammatory cytokines by specialized white blood cells called macrophages. (Katsanos et al, 2018). It is a life-long disease which can … Read more

Medical Waste Management

CHAPTER II REVIEW OF RELATED LITERATURE The value of medical waste management in the protection of public health and the environment cannot be denied (Thakur and Ramesh, 2015). One concern in the society nowadays is the inadequate treatment and improper disposal of medical wastes in various medical facilities due to the harmful effects of such … Read more

Personalised medicine

In a large patient population, a medication or a drug that is proven to be efficacious in most of the patients usually fails to work in some other patients. Moreover, when the medication does not work, it may cause severe side effects and sometimes may cause death. Drug efficacy and safety variability between patients have … Read more

The advancement of medicine

The start of medicine is hazy, cave drawings and other historical artifacts show ancient civilizations having a wise elder which people consulted for medical advice. There were various traditions, some effective but mainly most were based around spells curses spirits demons and other supernatural creatures. Around the 11th century the Islamic world had made a … Read more

Surfactants (surface active agents)

Surfactants (surface active agents) are amphiphilic compounds which have the ability to reduce the surface tension of two phases; liquid and liquid, liquid and gas or liquid and solid.1 It is important to note that not all amphiphiles behave as surfactants, only those with somewhat equilibrated hydrophobic and hydrophilic regions.2 Principally, surfactants are made up … Read more

Nursing

Nursing as a profession of front line care, requires not only scientific knowledge procured through study, but most importantly a high level of interpersonal and practical skills. All components of communication; verbal and non-verbal are essential prerequisites in meeting the needs of patients and their families as well as integral parts of nursing such as … Read more

Rate of discovery of new drugs

Over the years, the rate of discovery of new drugs has declined significantly, leading to an urge to explore alternative environmental sources apart from the soil, for novel antibiotics. In this study, water samples were collected from different places around Bath and they were screened for antibacterial activity against six test bacteria. A total of … Read more

Antioxidant and Hepato-protective effect

Antioxidant and Hepato-protective effect of Desmodium gangeticum (L.) DC. ethanolic extract in Streptozotocin induced rat model of diabetes mellitus   Abstract: Ethno-pharmacological relevance: Desmodium gangeticum (L.) DC.(DG) is well explored and well documented traditional Indian medicinal plant used to treat various ailments like neurological imbalances, anti-diabetic, anti-leishmanial, anti-inflammatory etc. , Aim of the study: To … Read more

USE OF HAPTEN-CARRIER COMPLEXES

USE OF HAPTEN-CARRIER COMPLEXES FOR BENZIMIDAZOLE PESTICIDES IMMUNOASSAYS DEVELOPMENT   Abstract In order to develop immunoassays for pesticides detection, this work describes the choice of three different haptens that present structural similarity to benzimidazole molecule, methods for coupling them with two carrier proteins in order to make them immunogenic, a protocol for immunization of laboratory … Read more

Counterfeit drugs in community pharmacies

Abstract This study seeks to determine the prevalence of counterfeit drugs in community pharmacies, patent medicine vendor drug distribution outlets and drug consumers in Cross River State. A cross- sectional descriptive study design will be applied in this research and data will be collected from important drugs randomly selected from community pharmacies and patent medicine … Read more

To what extent has the practice of medicine reinforced health inequalities among minority ethnicities?

Introduction In the event of recent years many politicians have said that Britain is on its way to becoming a multicultural country, due to the ever increasing number of ethnicities that live within the city of London and throughout the country. “Britain is a radically more diverse society than it was in the 1960’s, with … Read more

Stem Cell Transplant

1. Introduction: – Stem Cell Transplant: All blood cells in the body start as immature, young, cells “Hematopoietic stem cells, meaning blood-forming cells. Most stem cells live in the bone marrow, and then they divide to form new blood cells and stay in the bone marrow until they are mature. Once they are mature, they … Read more

Hepatogenic Differentiation of Human Induced Pluripotent Stem cells

Abstract Induced pluripotent stem cells (iPSCs) have attracted the attention of many surgeons and scientists for cell replacement therapies. Nanofibrous biocompatible scaffolds have been shown to promote better cell adhesion and improve stem cell differentiation. In the present study, after fabrication using electrospinning technique and surface modifications, the characteristics of Polyethersulfone (PES) nanofibers were determined … Read more