Parkinson’s disease progression, cause and treatment

Parkinson’s disease (PD) is a neurodegenerative disorder that affects predominately dopamine-producing (“dopaminergic”) neurons in a specific area of the brain called substantia nigra. Parkinson’s disease affected one in 100 people over the age of 60, the average onset is 60 years old. For this degenerative disease the symptoms develop slowly over the years. The progression … Read more

Geophagy in Pregnant Women

PICA is an eating disorder characterized by the consumption of nonnutritive substances. One category of PICA is geophagia (or geophagy), the consumption of dirt, soil, or clay. Geopaghy has been recorded in 1000 AD and most countries have populations (in both animals and humans) have been found to consume it.1 Currently, geophagy is found most … Read more

Infantile hemangioma (IH) – use of oral Propranolol

Focused Clinical Question: In patients ages six weeks to five years old with an infantile hemangioma (IH), does treatment with oral Propranolol decrease the redness and rate of growth of the hemangioma in comparison with the patients who receive a placebo treatment? Summary of search, “Best Evidence” Appraised, and Key Findings • The literature was … Read more

Diagnostic accuracy of conventional ultrasound in differentiating between benign and malignant thyroid nodules

Title An evaluation of the diagnostic accuracy of conventional ultrasound (US) in differentiating between benign and malignant thyroid nodules in adult patients, using fine needle aspiration cytology (FNAC) as reference standard: a protocol for a structured literature review. Aim Examine the accuracy of conventional ultrasound in differentiating between benign and malignant thyroid nodules using the … Read more

Relationship between multidisciplinary team meetings and patient survival

Examining the potential relationship between multidisciplinary team meetings and patient survival in pediatric oncology settings: a systematic review. Abstract Background The organization of multidisciplinary team meetings (MTMs) has become standard practice in contemporary cancer care. They cost considerable time and resources. Although the impact of MTMs on survival in adult oncology has been well researched, … Read more

Leishmaniasis (draft)

A vector-borne, protozoan parasitic disease, Leishmaniasis is transmitted by the bite of more than 70 different infected phlebotomine sand fly species carrying any of over 20 Leishmanial parasitic variants.8 Additional reservoirs include rodents, canines, and humans. 8 It is prevalent in over 90 countries, tropical and subtropical, throughout the Middle East, North Africa, Central and … Read more

Haemolytic Uraemia Syndrome

1. Summary of Recommendations: Haemolytic uremic syndrome (HUS) is a condition that affects the blood and blood vessels resulting in destruction of blood platelets, anaemia and kidney failure. There are two types of HUS; Typical (cause by infection) atypical (usually genetic default). In this essay aHUS is referred to as Complement-mediated TMA, to emphasise the … Read more

How much sleep should a person get each night?

How much sleep should a person get each night? According to the National Heart, Lung and Blood Institute, the answer to this question for teenagers and young adults is a minimum of 8 hours per night. Many underestimate the effects that a lack of sleep can have on one’s brain and bodily functions. The lack … Read more

Autism spectrum disorder (ASD) and technology

Because we live in a world made up of complex sensory information, one of the important challenges of the brain is to filter and synthesize this information in order to guide behavior and shape perception. Stimulation through multiple senses often allows appropriate behavioral responses to be generated under circumstances in which information from one sense … Read more

Leukaemia risk factors, diagnosis and treatment

Leukaemia is a cancer of white blood cells. White blood cells are important for the body to fight infections and these blood cells form in the bone marrow. The bone marrow produces abnormal white blood cells and the cells crowd and block out the healthy blood cells, making it hard for the healthy ones to … Read more

Lung agenesis

Successful development of a functional lung involves multiple biochemical and physical processes. The process of lung growth starts to occur at the 4th-5th week of gestation and reaches maturity by the 36th week. Any pathologic insult to any level of lung development may cause disruption of pulmonary growth. The exact etiology of pulmonary agenesis has … Read more

MIT therapy research

The research related to this paper started with an interest in aphasia. From there it developed into a specific type of treatment for aphasia. I ultimately chose to dive deeper into the research of melodic intonation therapy (MIT). This seems to be an emerging topic in the field of speech-language pathology. When conducting a PubMed … Read more

Achondroplasia – current treatments and research

Achondroplasia is a genetic disorder and the most common form of dwarfism that is characterized by disproportionate short stature, a prominent forehead, midface hypoplasia, and trident hands (Harada et al., 2017, p. 874). According to a 2012 Genetics Home Reference article titled “Achondroplasia,” the skeleton is mainly composed of cartilage during early life, and sometimes … Read more

Becker nevus

Becker nevus is a nevoid melanosis, that can cause a significant esthetic problem, and when is associated with other anomalies like musculoskeletal anomalies and ipsilateral hypoplasia of the chest or limb, it’s called Becker nevus syndrome. An association has been seen with bone, vascular and neural anomalies. Other non-cutaneous abnormalities associated with Becker nevus are … Read more

Post-Traumatic Stress Disorder

Brief Overview The fifth edition of the Diagnostic and Statistical Manual, fifth edition defines Post Traumatic Stress Disorder (PTSD) as a mental condition or psychological distress which happens to someone after experiencing or witnessing a traumatic or nerve-wracking event. (DSM-5, 2013) Faust & Ven (2014) found that PTSD may occur as a result of one … Read more