Imagine, you could go to the clinic and choose on a menu what kind of traits you would like for your child? Green eyes, brown hair, a high IQ and a kind and generous personality? Is this really possible in the future? Can we edit out bad genes that cause diseases in humans and replace them with healthy ones? Is this ethical and technically possible? Could we engineer animals so they can’t pass on deadly diseases to us?
Is this all ethical and technically possible?
All these questions made me want to choose the topic surrounding genetic modification, and specifically designer babies. it excites me to think about the new technology known as CRISPR- which makes it theoretically possible to change the genes in human-DNA.
I decided to write my PWS in English, because most of the articles that are published about this technology are all in English. On top of this, I liked the opportunity to prepare a project like this in English because we normally don’t get that chance.
1 What is CRISPR?
CRISPR gene editing technology is seen by many scientists as a way in the future to cure cancer, prevent the passing on of inherited diseases and viral infections.
1.1 – DNA info + Definition CRISPR:
Before I explain further to you about CRISPR, I’ll give you some information about DNA, as this is an important part of the whole research. DNA is also known as the molecule, or code of life, called by the name Deoxyribonucleic acid. A complex molecule that guides the growth, development, function and reproduction of everything alive. Information is encoded in the structure of the molecule, 4 nucleotides are pared and form a code that carries instructions, change the instructions and you change the being carrying it.
DNA, code of life
CRISPR’ stands for “Clusters of Regularly Interspaced Short Palindromic Repeats.” The name refers to the way short repeated DNA sequences in the genomes (the complete set of genes or genetic material present in a cell or organism) of bacteria and other microorganisms are organised. The popular term “CRISPR” is short for “CRISPR- cas9.” This “cas9” is an enzyme that acts like a pair of molecular scissors, capable of cutting strands of DNA.
1.2 – How does the process work?
CRISPR technology is made up of two elements, an enzyme and a guide molecule. The guide molecule takes its enzyme (Cas9) to a gene which is selected for modification, the enzyme cuts the gene which can then be repaired or modified in many different ways. By using CRISPR technology it is possible to change the function of the gene, remove the gene altogether or make the gene more active.
How the genome editor works
In this picture you see that The CRISPR-Cas9 system targets precise gene sequences and removes, adds to, or changes them with the help of two components: an enzyme called Cas9 and guide RNA (gRNA). It’s based on the naturally occurring ability of bacteria to recognize and
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