Chromosomal organization, gene regulation & treatment for disease

Introduction Since the discovery of genes, scientists have always been aware that they are probably more complex than they thought (Raf 1996, Davidson 2001). How the nucleus was responsible for regulating gene expression was always of great scientific interest (Cremer & Cremer, 2001). Chromosomes were found to be organized in discrete territories. Genes that are … Read more

Genes, gene expression, mutations and disorders

Gene To understand the gene, we must first start by understanding the structure of DNA [1]. The double-helix structure of the Deoxyribonucleic Acid (DNA) was first proposed by Watson and Crick in 1953[2]. DNA is a macromolecule that encodes the genetic instructions necessary for coordinating cellular life in all organisms both prokaryote and eukaryote, except … Read more

The selective autophagy of viruses

Abstract Autophagy is an evolutionarily conserved and highly regulated, intracellular catabolic mechanism that is important for maintaining homeostasis and coping with nutrient starvation. It is increasingly appreciated that autophagy can be highly selective, and that xenophagy, the selective autophagy of pathogens, is an important aspect of the immune response and protects against infection. This project … Read more

The effect of charge on polymersomal drug delivery systems

1.0 Introduction In recent years, new APIs have increasingly reduced in solubility and is estimated that approximately 70% of new chemical products possess low solubility in both aqueous and organic environments.1 This has led to one of the main confronts of the pharmaceutical industry, proving that effective drug delivery systems are as essential as pharmacodynamics … Read more

Blood – functions, components and structure

All human and animal need blood to stay alive. Blood is a compounded substance that carries different cells and substances to all part of the body. The movement of blood into the artery system depend on the different pressure at which the heart beats.Blood is like a simple thick fluid which is dark red in … Read more

Gold Nano particles and quantum dots in the diagnosis of breast cancer

Comprise advantages and disadvantages of gold Nano particles and quantum dots in the diagnosis of breast cancer by biding to Her-2 and Ki 67 antibodies Abstract Today, breast cancer is the most widespread cancer among women and each year, many women will die from this disease. For this reason, the diagnosis of breast cancer in … Read more

Mos kinase

INTRODUCTION: 1.1 ABOUT MOS KINASE: Mutation in a single cells causes cancer over a period of time in a person’s life. The genes that play a role in causing cancer are: a) tumor suppressor genes b) proto oncogenes Mos is a proto oncogene that is responsible for coding the serine/threonine kinase. In 1980 ,the transforming … Read more

Gamma irradiation method in nanotechnology

Recently, the nanomaterials (the metal nanoparticles or polymer/metal nanocomposites) are the subject of increased attention of researchers in different areas of science and technology, due to its applications in many fields in our life such as solar cells, novel photodiodes and sensors. So, the synthesis routes of these nanomaterials have a much interest from the … Read more

Electrodes

The Electrochemistry is defined as a branch of chemistry which deals with the properties and behavior of electrolytes in solution and the inter-conversion of chemical and electrical energies. Derivation of Nernst equation for electrode potential The Nernst Equation is used to determine the single electrode potential of the cell. The Nernst Equation is derived from … Read more

Aspects of mitochondrial membrane-bound arginase

Arginase, member of ureohydrolase family, catalyses arginine into ornithine and urea. As a classical molecule, arginase involved in nitrogen detoxification as it is majorly reported in the hepatic tissue of ureotelic organisms (Clementi, 1937), later on, arginase reported in mitochondria of extra hepatic tissues of fungi, plants, invertebrates and vertebrates where it appears to be … Read more

Production of polygalacturonase

1.0 Introduction Plant cell walls can have up to three different layers; primary cell wall, secondary cell wall and middle lamella. The middle lamella which is rich in the polysaccharide pectin forms the outermost layer of the cell wall that separates the cell from its adjacent cells. The main composition of pectin is galacturonic acid … Read more

Augmenting PGPR and PGPF groups in a Wicking bed system

Background Agroecosystems are been studied extensively for the presence of the beneficial Plant Growth Promoting Microbes (PGPM), and their beneficial role in plant growth and health. PGPM, consisting mainly of two different groups – Plant growth-promoting Rhizobacteria (PGPR) and Plant growth-promoting Fungi (PGPF), colonize the roots or the Rhizosphere area of the plants in a … Read more

Preparation and test of different draw ratios cast film

As more and more electric devices are entering into our life, especially the demand of electric vehicles is increasing. So rapid development of EV or HEV requests high power Li-ion batteries (LIBs) to have higher energy, longer life and better safety than before. The process of producing microporous membrane is melt-extrusion/annealing/uniaxial-stretching (MEAUS), which is a … Read more

The scientific revolution

The scientific revolution was a time period that spun over two centuries and included a series of discoveries in the field of science and mathematics that revolutionised the way the world was perceived from that moment forward. Opening many doors into what the future held, it also solved the unspoken mysteries of the past. Several … Read more