Investigate the effect of Saroglitazar on myocardial ischemia

Ischemic heart disease is the leading cause of the death worldwide, according to the third monitoring report of the World Health Organization cause 12 million death throughout the world each year. Approximately 1.5 million cases of myocardial infarction occur annually in the United States; yearly incidence rate is approximately 600 cases/1, 00,000 people.[1] Myocardial infarction … Read more

Urotensin II (U-II)

Urotensin II (U-II), a potent mammalian vasoconstrictor peptide, was initially isolated and characterized from the Gillichthys mirabilis (goby) urophysis (Pearson et al., 1980). Later, human U-II cDNA was cloned, and hU-II appeared as an eleven amino acid peptide with cysteine residues in positions 5 and 10, forming a disulfide bridge through their side chains (Coulouarn … Read more

Metal foams

Metal Foams are a cellular structure comprising of a solid metal containing a large capacity portion of gas filled pores. The solid metal structure is most commonly made from aluminium, titanium or tantalum. The gas filled pores can come in two forms, closed-cell foam and open-cell foam. Closed-cell foams have a distinct honeycomb effect. They … Read more

The polymerase chain reaction (PCR)…

The polymerase chain reaction (PCR) includes the use of two fragments of DNA, whether they are primers or oligonucleotides, to make two molecules of nucleic acid amplify and therefore synthesis of a specific region of DNA(1). The DNA sample first altered to make the DNA double helix of two single strands(1). This happens by putting … Read more

Genetic engineering

Genetic engineering is a technique involving the manipulation of an organism’s genome through the insertion of a gene, removal of a nucleotide sequence or alteration of a gene’s ability to express itself. The resultant being, a genetically modified organism is a major source of nutrition in the contemporary world. The year 1994 marked the dawn … Read more

Infertility factors in men

Introduction It is not possible to find a cause of infertility in nearly 50% of infertile men and this situation has been defined as unexplained or idiopathic (Iammarrone et al. 2003). The role of trace elements in sperm and whole semen quality may have significant influence upon men infertility (Abou-Shakra et al. 1989). Some metals … Read more

Studying neuroscience

SPECIFIC PURPOSE: I want my audience to better understand aspects of the neuroscience major. THESIS: Neuroscience is my choice of study because the brain is a fascinating, complex organ with many unknown capabilities. INTRODUCTION ATTENTION GETTING DEVICE: Did you know that the brain has a consistency similar to tofu? A brain may look mushy or … Read more

Chitosan nanoparticles

Wang et. al. carried out the study on the estradiol(E2)-loaded chitosan nanoparticles (CS-NPs). The nanoparticles were prepared by ionic gelation method and had a mean size of (269.3 ?? 31.6) nm and zeta potential of +25.4 mV. Loading capacity of the E2 CS-NPs suspension and entrapment efficiency was found to be 1.9 mg/ml and 67% … Read more

Electrons

Many physical phenomena , such as electricity, magnetism, and thermal conductivity etc., involve electrons in the main role. They are said to be everywhere. However, no one has ever seen an electron. “Seeing” an electron has no physical meaning, as the wavelength of light is much larger than the “size” of the electron. This means … Read more

Persistent organic pollutants (POPs)

Persistent organic pollutants (POPs) are the organic compounds which can persist for longer time in the environment. They are toxic, persistent, and bioaccumulative in human and animal tissue and biomagnify in food chains and tend to long-range transport. They have long half-lives in soils, sediments, air or biota. The half lives generally depend on the … Read more

Metabolites formed in vivo

1: Systemic levels of the chemical entities can be observed within 2 to 3 hours. Compound A ethyl pyrazole ring attached to oxo pyramidine ring attached to benzyl solfoxo piperazine. Compound B has dioxypiparazine ring and a dioxybenze and a indole. The major p450 metabolism for both the compounds will be demythylation. Compound A can … Read more

Cell structure

The plant cell protoplast is enclosed by a fibrous wall that grows as the cell expands to its mature size, but which becomes cross-linked and eventually limits the growth of the cell, defining and supporting the cell and collectively providing support for stems and lives. Some cells, like photosynthetic and storage cells, only have a … Read more

Biosynthesis

Biosynthesis is an economic alternative over chemical and physical methods for the synthesis of metal nanoparticles [1]. The nanoparticles were extensively used in consumer products such as tires, textiles, cosmetics, food industries and in medical devices [2]. Several approaches are in practice to generate AgNPs, such as, chemical, electrochemical, photochemical and radiation [3-6]. However, still … Read more

Defining the scientific field and objectives of biomimicry

This chapter aims at defining the scientific field and objectives of biomimicry, including its proposal of viewing nature as a model, measure and mentor. Furthermore, the overarching principles found in all forms of life will be elucidated. Concerning cities, an inclusive perspective, viewing humans and their creations as part of the larger ecosystem will be … Read more