Potential novel relationship between Rgnef and the SHH pathway
Introduction Neural tube defects (NTDs) are severe birth defects of the central nervous system and refers to failed neural tube closure during embryonic development (Ghi et al., 2018). The phenotype presented by those with NTDs is dependent on where the neural tube remains open (Copp and Greene, 2010). Therefore, the seriousness of disease manifestation varies. … Read more