Genetic Alterations And Cancer

Microsatellite instability is an indicator of defects in DNA mismatch repair genes. These genes functions as tumor suppressors, upon inactivation implies defective mismatch repair pathway and dramatically increase replicative error rate

Cervical Cancer

Cervical cancer is one of the most common cancers in low-income countries like Bangladesh accounting for 23% of all cancers respectively (Parkin et all, 2008)