Role Of Narcotic Component Of Drugs
Understanding Narcotic Drugs
Many of the people use the term of narcotics to referring as- to the all types of controlled substances. Some of the people incorrectly believe that- narcotics are simply illicit or illegal drugs. However, narcotics are a particular type or class of drug that affects the human brain and that are highly addictive.
Some narcotics are called legal and some are called illegal. For example- Vicodin, Oxycontin, and codeine are doctor prescription type of narcotics that are called legal when we taken as prescribed form. However, when a user takes these types of a medication that was prescribed for someone else or in a manner that not intended by the hand of prescribing doctor, it is known as prescription narcotic drug abuse. Prescription narcotic drug abuse/misuse is the illegal use of a legal drug. There are also illegal types of narcotic drugs such as- heroin. All possession/occupancy and use of heroin is strictly prohibited in the law of our state.
Whether it is legal or illegal, narcotics are the pain relieving/reducing drugs that work by affecting certain types of receptors in the user's brain and dulling/dullness the user's sense of pain. They affect the same type of receptors that tell the human brain really it’s experiencing mental pleasure and reward. Many of the drug abuse/misuse experts cite this – as the main reason narcotics are one of the most widely abused or addicting drugs.
Classification Of Narcotic Drugs According To Their Origin: Narcotics are commonly classified into three groups according to their origin. These are followings:
01. Natural Derivatives of Opium: Narcotics in this group includes:
Morphine itself and
Codeine.
02. Partially Synthetic Drugs Derived From Morphine: These drugs includes-
Heroin
Oxycodone (OxyContin)
Hydromorphone (Dilaudid) and
Oxymorphone (Numorphan)
03. Synthetic Compounds That Resemble Morphine In Their Chemical Structure: Narcotics in this group includes-
Fentanyl (Duragesic)
Levorphanol (Levo-Dromoran)
Meperidine (Demerol)
Methadone and
Propoxyphene (Darvon)
Narcotics are available in many different physical forms, that ranging from different oral forms, intramuscular forms and intravenous preparations to patches that can be applied or uses to the skin (fentanyl). Illegal street heroin can be taken by the process of inhalation as well as by the process of injection.
List of Some Potent Narcotic Drugs
There are many of the different types of narcotics drug each of which has similar type of effects but may be manufactured it’s differently or prescribed for the different purposes. While most of the narcotics drugs are simply prescribed for the purpose of treatment of moderate to severe type of pain, there are some other uses such as- to inducing sleep or to reducing cough. Narcotics are widely available drugs in both of the street forms and in legal prescription ways of medications.
Common Narcotics
The following list of the narcotics drugs is only just a sample of some of the names that we may hear either in a medical setting or on the streets:
• Heroin
• Opium
• Oxycontin
• Oxycodone
• Hydrocodone
• Hydromorphone
• Fentanyl
• Buprenorphine
• Levorphanol
• Codeine
• Lorcet
• Lortab
• Norco
• Oncet
• Procet
• Vicodin
• Xodol
• Zydone
This is just for a partial part of list as there are many type of drug that include combinations of this medications in them which are also considered as narcotics drugs. The term narcotics is actually used to referring to nearly any illegal/illicit drug in some of the areas but the true meaning is an analgesic such as- prescription types of painkillers/pain reducing analgesics. Some of the states or users are described narcotics as just about for any type of drug that including cocaine or methamphetamine like.
On the other hands, Narcotics are typically those of the drugs which are either directly taken from the opium poppy such as- heroin or morphine as well as the long list of opioids that are either synthetic/semi-synthetic parts, which means that all or a portion of the drug is created in a laboratory setting. Heroin or morphine and prescription by doctor painkillers continue to be the mostly and widely known as narcotics.
Some of the areas also include list of barbiturates and benzodiazepines considered as the narcotics drugs. These are includes:
Benzodiazepines:
Xanax
Paxal
Klonopin
Valium
Diazepam
Lorazepam
Ativan
Alprazolam
Barbiturates:
Vesparax
Soneryl
Fiorinal
Fioricet
Prominal
Mebaral
Bervital
Lotusate
Regardless of whether, the list of narcotics drugs including only the opiate based drugs that are derived from the plant of poppy or if, it includes other dangerous type of drugs such as- barbiturates or benzodiazepines, these type of drugs all carry a wide potential for causing growing dependence and subsequently physical addiction which is actually difficult to control and equally difficult to treat of that.
Mode of Action of Narcotic Drugs:
The central nervous system in humans contains five different types of opioids receptor- proteins, which is located or situated primarily in the human brain; spinal cord and the digestive tract or GIT. When, a person taking/administered an opioid medication, the drug attaches to these types of opioid receptors in the brain and spinal cord and decreases the person’s perception of pain sensation. Narcotics do not, however, reduce or eliminate the cause of the pain sensation.
Some of the opioid receptors known as mu and sigma receptors influence a person’s perception of the state of pleasure. When a narcotic medication stimulates these receptor proteins, the person typically experiences the intense sensations of euphoria or the state of well-being. The speed with which these drugs take effect, that depends on the method of administration, IV route narcotics reach their peak label of effectiveness within ten minutes, while oral route narcotics take about one hour duration and a half hour duration of time and the skin patches takes between two to four hours duration of time.
Overdoses of narcotics can cause for drowsiness, unconsciousness and even death because, these drugs suppress the respiration.
Effects of Narcotic Drugs On The Human Mind
When prescribing forms of narcotics are taken in recommended doses, the user likely won't experience many of the noticeable effects, outside of the pain relief. However, there are several obvious visible effects when narcotics are taken in the amount of high doses. Initially, the user of narcotics drugs may feel a sense of euphoria or state of intense excitement and happiness, which is also known as- an intense type of feelings of elation and excitement. Euphoria is most extreme for the users who inject or snorting narcotics.
Others producing psychological types of effects of narcotics drugs includes:
Calm/relaxed feeling
Reduced/Relieved anxiety
Hallucinations or psychosis
Positive types of outlook
Feeling as if, the user cannot get through the day without narcotics
Narcotics are highly addictive drugs because, many of these psychological effects are perceived to be positive by the user. However, users quickly develop a physical tolerance, which means the user needs a higher or large dose in order to achieve the desired effect. Higher/large doses and prolonged durational use of narcotics come with greater risk.
Effects of Narcotic Drugs On The Human Body
When we talk about the risks involved with the uses of narcotics, we are generally talking about the effects on the human body. Narcotic drugs have several and different types of effects that found/viewing on the person’s body, who actually are addicted/abuse on that drug, in the followings:
Sedation/drowsiness
Slowed/slowing movement
Delayed reactions and lack of co-ordination
Nausea and vomiting
Constipation, reduced appetite and other stomach ailments
Reduced pain
Constricted pupils
Itchiness/other skin irritations
Dry mouth and dehydration
Difficulty/shallow in breathing
Reduced heart rate
Brain disorders/brain damage from extended use
Collapsed veins/scarred veins from injections
Infections and diseases caused by the use of shared/ using dirty needles, such as HIV and hepatitis, endocarditis etc.
Addiction in the pregnant women that can lead to premature baby/stillborn or addicted infants who experience severe withdrawal symptoms.
Seizures
Coma
Death
Again, narcotics are called highly addictive drug, therefore, users often develop state of dependency over the narcotics drugs. Dependency occurs when the body of narcotics user's becomes used to the presence of a drugs and that needs it, in order to functional capacity.
Effects Of Opiates On The Human Body At The Neurochemical Basis:
Opiates block the pain signals to the user's brain while also stimulating pleasure signals. Opiates accomplish this by the affecting neurotransmitters systems. The neurochemical basis for the opiate effects are explains shortly in the followings-
Opiates
More or less everybody may have heard of opium. It is an ancient drug made from the seed pods of the poppy. Opium was typically smoked or inhaled and was often it is used in rituals before becoming popular in many of areas of the world considered as- most recreational types of drug. Opium or opioids was prized for the centuries as a painkiller drugs/pain reducing prescribing drugs and producing a sedative action, but among many of cultures quit using opium as a medicine due to widespread abuse of the drug.
There are many relatively newer drugs which derived directly from opium and designed to have the same pain relieving/reducing effect. These are known as opiates. Codeine and morphine are known as opiates. Heroin is also an opiate, though heroin has been illegal and strongly prohibited in the law of our state.
Note that, opiates are narcotics. Narcotics are specific type of drugs that works by affecting the person of user’s brain and dullness the user's body pain sensation. Opiates or opioids block the pain signals to the body of the user's brain while stimulating of the pleasure signals.
Neurotransmitters
Let's take a closer look at how the opiates affected the user's brain. Opiates work by the influencing of the user's neurotransmitters. Neurotransmitters are the naturally occurring brain chemicals that communicate information at throughout the user's brain and body. Peoples have many different types of the neurotransmitters. For example- One type of the neurotransmitter tells our eyes to cry, when we are in sad, and another type tells our stomach to growl, when we are in hungry.
Neurotransmitters conduct signals between the neurons and the receptors of the human brain. A neuron produces/propagate and sending a message/information and the receptor receives this message/information. Signals can’t be sent between a neuron and a receptor without the uses of neurotransmitters because, the two don't connect. There is a tiny space in between each neuron and receptor known as a synapse. Neurons send neurotransmitters towards the synapses/nerve cells junctions. The neurotransmitters are then accepted or adopted by and attached to the receptors of the human brain with other parts where it is located.
In the fact, the human brain naturally contains special receptors that designed to help opiates or opioids work. They are called as opiate or opioids receptors. These types of receptors are concentrated in the areas of the brain that recognize the person’s pleasure and reward. The same types of receptors are also concentrated in the areas of the body that recognize/identify pain, such as the brainstem and spinal cord of the human body.
Endorphins
Opiate receptors are likely exists because, the human body produces- natural opiates, that known as endorphins. Endorphins are the neurotransmitters that are released when the human body experiences pain or stressful condition. They work to calm the human brain. Endorphins are attached to the opiate or receptors.
Depending on how much stress/pain a person experiences/realized, sometimes more of the endorphins are released than can attach. This causes a traffic jam conditions of endorphins in the synapse/nerve cells junction area, which blocks the other types of signals from passing through its. The neurons will stop firing in temporarily/trying to send messages towards the synapse. This hinders pain signals and can bring about an overall numbing/paralyze effect.
The pain relieving/reducing effect of opiates is achieved by mimicking endorphins. Opiate molecules flood/overflow into synapses and attach to the opiate receptors, thereby blocking the pain signals.
Dopamine
Opiates also influence a neurotransmitter known as- dopamine. Dopamine is a naturally occurring chemical that releases into the brain to bring about person’s feelings of pleasure and reward. For example- dopamine releases into our brain, when we laugh at a funny joke or when we eat our favorite dessert. It is a special type of the neurotransmitter, because it capable works to both stimulate/excite and calm the human brain at the same duration of time. Other neurotransmitters do one or the others, but not for it both.
Narcotic Drug Interactions
Narcotics drugs can be dangerous because of their potentiality for deadly interactions with the other medications as well as their potential for the dependence and addiction. Narcotics drugs should never be combined with the other types of drugs that are always depress the central nervous system (CNS). These categories of the drugs included in the followings:
Alcohol
Benzodiazepine tranquilizers, including such of the drugs as- Diazepam (Valium)/Alprazolam (Xanax)/Chlordiazepoxide (Librium)
Barbiturates, that used to treat insomnia and the state of anxiety, including such types of medications as- Pentobarbital (Nembutal) and Mephobarbital (Mebaral)
Antihistamines, even over the counter cold or for the allergic medications, which can directly interact with the narcotics drugs to intensify drowsiness and repress/depress breathing.
Narcotics drugs can also interact with the certain herbal preparations to cause central nervous system (CNS) depression. Anyone taking narcotics drugs for the purpose of pain relief, should avoiding using of herbal preparations that likes- containing kava kava (Piper methysticum)/ valerian(Valeriana officinalis)/chamomile (Matricaria recutita)/lemon balm (Melissa officinalis) as these herbs or herbal preparations intensify the tendency of opiates or opioids to cause producing drowsiness and slowing down breathing. Herbal preparations- Ginseng (Panax ginseng) should also be avoided because it strongly interferes with the pain- relieving/reducing qualities of opiates or opioid medications.
Narcotics Abuse
When peoples use narcotics drugs only to control/relieve pain, they are unlikely to become addicted/abuses to the drugs. However, opiates or opioids provide high intoxicating effects, when it’s injected or taken orally in high amount of doses. Opioids or opiates are also powerful anxiety relievers/reducers. For these reasons, narcotic drugs addiction/abuse is one of the most common forms of drug abuse in around whole of the world. Terms like opiates or opioids abuse, drug abuse/misuse, drug dependence/ dependence on drugs and drug addiction are often used interchangeably, but most of the experts define them are as following ways:
• Drug Abuse: Drug abuse/misuse, including opioid abuse/misuse, is the deliberate use of a medicine beyond a doctor's prescription form. In the case of opiates or opioids, the common intention is generally to get high or to relieve/reduce anxiety.
Symptoms of Narcotic (Opioid) Drugs Abuse:
Analgesia/pain relievers (feeling no pain)
Sedation
Euphoria/ state of intense excitement and happiness (feeling high)
Shallow/slow breathing
Respiratory depression
Small pupils
Nausea, vomiting
Itching/flushed skin
Constipation
Slurred speech
Confusion/poor judgment
• Drug Dependence: Dependence only occurs when the body of user’s develops tolerance to the drug, that meaning higher doses of these types of drugs are needed for producing the same effects. In addition, stopping these types of drug produces an effect known as- drug withdrawal symptoms.
Symptoms of Narcotics (Opioids) Drug Withdrawal From Dependent Body:
Anxiety
Irritability
Craving for the drug
Rapid breathing
Yawning
Runny nose
Salivation
Goosebumps
Nasal stuffiness
Muscle aches
Vomiting
Abdominal cramping
Diarrhea
Sweating
Confusion
Enlarged pupils
Tremors
Loss of appetite
• Drug Addiction: Addiction occurs when the person has dependence on drugs, but also displays psychological/mental effects. These includes compulsive/addictive behavior to get the drug/craving for the drug and continued using this type of drugs despite the negative/bad consequences, that create different types of legal problems or that are strongly responsible for violation of the laws and regulation of our society, with the state; such as- breaking study, breaking of relationships or divorce, unwanted familial hazards and facing trouble, distance from loving personnel, self destruction, suffer from different health hazards, losing a job, or facing others minor/major punishments, suffer from severe mental stress, different types of anxiety, depressions, finally take decision of suicide is the visible example for that.
So, Growing dependence on narcotics (Opioids) drugs is the key factor for addiction; which are responsible for produces different types of psychological effects, and make compulsion to take drug of an addict or a narcotic drugs abusers.
Thus, Addiction and Addictive Behaviors – Where Narcotic component of drugs producing effects on the human brain in negative consequences and play major role as a hijacking player.