Aligning Bisulfite Reads to a Reference Genome: Challenges and Solutions
Alignment of Reads from Bisulfite Treated DNA Samples Summary Sodium bisulfite treatment of DNA strands can detect methylated cytosines which can enable researchers to discover more information on the causes and effects of methylated cytosines. However, this produces many challenges with aligning bisulfite reads to a reference genome as the reference genome does not … Read more