Liddle syndrome
The epithelial sodium ion channel (ENaC) is a membrane-bounded ion-channel. It is permeable for Li+ and Na+-ions. ENaC is highly active and selective Na+ channel. ENaC plays an important role in trans-epithelial sodium ion transport. This Na+ reabsorption is accomplished by Na+/K+ATPase. In vertebrates ENaC controls Na+ reabsorption in kidney, colon, lung and sweat glands; … Read more